Müjde Eryılmaz1 
,
Merve Eylül Bozkurt1,
Muharrem Murat Yildiz2,
Ahmet Akin1
For correspondence:- Müjde Eryılmaz Email: mujdeyuce@yahoo.com Tel:+903122033185
Received: 11 September 2009 Accepted: 19 February 2010 Published: 15 April 2010
Citation: Eryılmaz M, Bozkurt ME, Yildiz MM, Akin A. Antimicrobial Resistance of Urinary Escherichia coli Isolates. Trop J Pharm Res 2010; 9(2):205-209 doi: 10.4314/tjpr.v9i2.13
© 2010 The authors.
This is an Open Access article that uses a funding model which does not charge readers or their institutions for access and distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0) and the Budapest Open Access Initiative (http://www.budapestopenaccessinitiative.org/read), which permit unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited..
Purpose: To investigate the antimicrobial resistance rate of 110 E. coli strains, isolated from UTIs in Etlik Lokman Hekim Hospital, Etlik, Ankara, Turkey.
Methods: API-20E System (bioMerieux, France) was used to identify E. coli isolates. Antimicrobial susceptibility testing was conducted on Mueller-Hinton Agar plates (Merck, Germany) using agar disc diffusion method and the results were expressed as susceptible or resistant according to the criteria recommended by the Clinical and Laboratory Standarts Institute (CLSI).
Results: The resistance rates detected were 56 % to ampicillin, 24 % to ampicillin sulbactam, 9 % to gentamicin, 15 % to ciprofloxacin, 36 % to trimethoprim sulfamethoxazole, 12 % to cefazolin, and 7 % to cefuroxime. All isolates tested were susceptible to fosfomycin and nitrofurantoin.
Conclusion: When the high resistance rates in Turkey are taken into consideration, antimicrobial agent usage policies and empirical therapies should be based on antimicrobial resistance surveillance studies.
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